Name : Shh Antibody / Sonic Hedgehog
Supplier : NJS POLY
Price :199
SKU : GEN5421686414
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Shh / Sonic Hedgehog |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | ELISA, WB, IHC |
| Recommended dilutions | IHC (Paraffin): 1:25, Western blot: 1:500-1:1000 |
| Notes | Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This Shh antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q62226 |
| Purity | Antigen affinity |
| Description | Also regulates another target, Displays both floor plate- and motor neuron-inducing activity, In the absence of SHH, Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, PTC represses the constitutive signaling activity of SMO, The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity), and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud, the gli oncogene, to activate the transcription of target genes, which functions in association with smoothened (SMO), Sonic hedgehog binds to the patched (PTC) receptor |
| Immunogen | This mouse Shh antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 397-431 amino acids from the C-terminal region of mouse Sonic hedgehog |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Shh antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Shh / Sonic Hedgehog |
| Short name | Shh Antibody / Sonic Hedgehog |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sonic hedgehog (Antibody to) / Sonic Hedgehog |
| Alternative technique | antibodies |