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SHIP1 Antibody, FITC Conjugated

SHIP1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, SHIP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSHIP1
SpecificityThis is a highly specific antibody against SHIP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SHIP1
Gene ID number3635
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background At the plasma membrane, Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation, Overall the protein functions as a negative regulator of myeliod cell proliferation and survival, an inositol phosphatase domain, and two C-terminal protein interaction domains, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3, thereby affecting multiple signaling pathways, 3, 4, 4, 5)-trisphosphate and inositol-1, 5-tetrakisphosphate, SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SHIP hp51CN SHIP1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSHIP1 Conjugated
Short name FITC Conjugated, SHIP1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SHIP1 (Antibody to)
Alternative techniqueantibodies
Identity 6079
Gene INPP5D
Long gene name inositol polyphosphate-5-phosphatase D
Synonyms gene name 145kD inositol polyphosphate-5-phosphatase, 145kDa , inositol polyphosphate-5-phosphatase
Synonyms name SH2 domain-containing inositol 5', -phosphatase 1
Locus 2q37, 1
Discovery year 1996-04-04
GenBank acession U57650
Entrez gene record 3635
Pubmed identfication 8643691 8874179
RefSeq identity NM_001017915
Classification Phosphoinositide phosphatases SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000133688

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