Name : SHOC2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1244623298
| Long name | SHOC2 Primary Polyclonal Antibody |
| Also known as | SHOC2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SHOC2 |
| Specificity | This is a highly specific antibody against SHOC2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHOC2/Sur8 |
| Gene ID number | 8036 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Affected subjects also have easily pluckable, NSLAH children display macrocephaly, Upon M-Ras/MRAS activation, high forehead, hypertelorism, low-set and posteriorly rotated ears, palpebral ptosis, short and webbed neck and pectus anomalies, sparse, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes, thin and slow-growing hair, Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) , Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | KIAA0862, Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Protein Sur-8 homolog, Protein soc-2 homolog, Ras-binding protein Sur-8, SHOC2, SHOC2_HUMAN, Leucine-rich repeat protein SHOC-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SHOC2 |
| Short name | SHOC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SHOC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15454 |
| Gene | SHOC2 |
| Long gene name | SHOC2, leucine rich repeat scaffold protein |
| Synonyms gene name | C, elegans) SHOC2 leucine-rich repeat scaffold protein , soc-2 (suppressor of clear, elegans) homolog soc-2 suppressor of clear homolog (C |
| Synonyms | KIAA0862 SOC2 SUR-8 SOC-2 SUR8 |
| Locus | 10q25, 2 |
| Discovery year | 2001-03-30 |
| GenBank acession | AB020669 |
| Entrez gene record | 8036 |
| Pubmed identfication | 9618511 9674433 10783161 |
| RefSeq identity | NM_007373 |
| Havana BLAST/BLAT | OTTHUMG00000019047 |
| Locus Specific Databases | LRG_753 |