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SHOC2 Antibody

SHOC2 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameSHOC2 Primary Polyclonal Antibody
Also known asSHOC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSHOC2
SpecificityThis is a highly specific antibody against SHOC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHOC2/Sur8
Gene ID number8036
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Affected subjects also have easily pluckable, NSLAH children display macrocephaly, Upon M-Ras/MRAS activation, high forehead, hypertelorism, low-set and posteriorly rotated ears, palpebral ptosis, short and webbed neck and pectus anomalies, sparse, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes, thin and slow-growing hair, Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) , Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA0862, Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Protein Sur-8 homolog, Protein soc-2 homolog, Ras-binding protein Sur-8, SHOC2, SHOC2_HUMAN, Leucine-rich repeat protein SHOC-2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSHOC2
Short nameSHOC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSHOC2 (Antibody to)
Alternative techniqueantibodies
Identity 15454
Gene SHOC2
Long gene name SHOC2, leucine rich repeat scaffold protein
Synonyms gene name C, elegans) SHOC2 leucine-rich repeat scaffold protein , soc-2 (suppressor of clear, elegans) homolog soc-2 suppressor of clear homolog (C
Synonyms KIAA0862 SOC2 SUR-8 SOC-2 SUR8
Locus 10q25, 2
Discovery year 2001-03-30
GenBank acession AB020669
Entrez gene record 8036
Pubmed identfication 9618511 9674433 10783161
RefSeq identity NM_007373
Havana BLAST/BLAT OTTHUMG00000019047
Locus Specific Databases LRG_753

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