Name : SHOC2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3453725354
| Long name | ALEXA FLUOR 488 Conjugated, SHOC2 Polyclonal Antibody |
| Also known as | Anti-SHOC2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SHOC2 |
| Specificity | This is a highly specific antibody against SHOC2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHOC2/Sur8 |
| Gene ID Number | 8036 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Affected subjects also have easily pluckable, NSLAH children display macrocephaly, Upon M-Ras/MRAS activation, high forehead, hypertelorism, low-set and posteriorly rotated ears, palpebral ptosis, short and webbed neck and pectus anomalies, sparse, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes, thin and slow-growing hair, Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) , Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KIAA0862 SOC2 SUR-8 SOC-2 SUR8 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SHOC2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | SHOC2 |
| Short name | SHOC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, SHOC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15454 |
| Gene | SHOC2 |
| Long gene name | SHOC2, leucine rich repeat scaffold protein |
| Synonyms gene name | C, elegans) SHOC2 leucine-rich repeat scaffold protein , soc-2 (suppressor of clear, elegans) homolog soc-2 suppressor of clear homolog (C |
| Locus | 10q25, 2 |
| Discovery year | 2001-03-30 |
| GenBank acession | AB020669 |
| Entrez gene record | 8036 |
| Pubmed identfication | 9618511 9674433 10783161 |
| RefSeq identity | NM_007373 |
| Havana BLAST/BLAT | OTTHUMG00000019047 |
| Locus Specific Databases | LRG_753 |