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SIAH1/2 Antibody, Cy7 Conjugated

SIAH1/2 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, SIAH1/2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIAH1/2
SpecificityThis is a highly specific antibody against SIAH1/2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range200-250/324
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human SIAH2
Gene ID number 6477, 6478
Swiss Prot Q8IUQ4, O43255
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BAG1), DCC), E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targets, NCOR1), PML, POU2AF1, SYP), Siah2 has some overlapping function with SIAH1 but is able to trigger the ubiquitin-mediated degradation of TRAF2, Siah2 triggers the ubiquitin-mediated degradation of many proteins, and proteins involved in synaptic vesicle function in neurons (e, antiapoptotic proteins (e, cell surface receptors (e, including transcription regulators (e, whereas SIAH1 can not, Siah2 is a E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of target proteins, g, g, g, g
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms hSIAH1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetSIAH1/2 Conjugated
Short name Conjugated, SIAH1/2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, siah E3 ubiquitin protein ligase 1/2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, SIAH1 and IDBG-30112 and ENSG00000196470 and 6477, SIAH1A, ligase activity, nuclei, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007049 and cell cycle and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0016874 and ligase activity and molecular function this GO :0030163 and protein catabolic process and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031648 and protein destabilization and biological process this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008022: protein C-terminus binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity, this GO :0005515: protein binding, this GO :0008022: protein C-terminus binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, 37798 and IDBG-631496 and ENSBTAG00000010868 and 534655, siah E3 ubiquitin protein ligase 1
Identity 10857
Gene SIAH1
Long gene name siah E3 ubiquitin protein ligase 1
Synonyms gene name seven in absentia homolog 1 (Drosophila)
Locus 16q12, 1
Discovery year 1997-09-12
GenBank acession U76247
Entrez gene record 6477
Pubmed identfication 9403064 9334332
Havana BLAST/BLAT OTTHUMG00000175417

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