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SIGLEC10 Antibody

SIGLEC10 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSIGLEC10 Primary Polyclonal Antibody
Also known asSIGLEC10 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSIGLEC10
SpecificityThis is a highly specific antibody against SIGLEC10
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC10
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In the immune response, It preferentially binds to alpha2, SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation, The protein is expressed by peripheral blood leukocytes (eosinophils, The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules, monocytes and a natural killer cell subpopulation), 3- or 2, 6-linked sialic acid, SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names SIGLEC 10, SLG2, Sialic acid binding Ig like lectin 10, Sialic acid binding Ig like lectin 10, Sialic acid binding Immunoglobulin like lectin 10, Siglec G, Siglec like protein 2, Siglec like protein 2, Siglecg, mSiglec G, sialic acid binding Ig like lectin 10 Ig like lectin 7, sialic acid binding Ig like lectin G, siglec like gene 2, PRO940
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSIGLEC10
Short nameSIGLEC10 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesialic acid binding Ig-like lectin 10 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, sialic acid binding Ig-like lectin 10
Identity 15620
Gene SIGLEC10
Long gene name sialic acid binding Ig like lectin 10
Synonyms gene name sialic acid binding Ig-like lectin 10
Synonyms SIGLEC-10 SLG2 PRO940 MGC126774
Synonyms name sialic acid binding Ig-like lectin 10 Ig-like lectin 7 siglec-like gene 2
Locus 19q13, 41
Discovery year 2001-06-29
GenBank acession AF310233
Entrez gene record 89790
Pubmed identfication 11284738
RefSeq identity NM_033130
Classification C2-set domain containing Sialic acid binding Ig like lectins V-set domain containing
Havana BLAST/BLAT OTTHUMG00000165521

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