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SIGLEC10 Antibody, ALEXA FLUOR 350

SIGLEC10 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, SIGLEC10 Polyclonal Antibody
Also known asAnti-SIGLEC10 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIGLEC10
SpecificityThis is a highly specific antibody against SIGLEC10
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIGLEC10
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen In the immune response, It preferentially binds to alpha2, SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation, The protein is expressed by peripheral blood leukocytes (eosinophils, The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules, monocytes and a natural killer cell subpopulation), 3- or 2, 6-linked sialic acid, SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms SIGLEC-10 SLG2 PRO940 MGC126774
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetSIGLEC10
Short nameSIGLEC10 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, sialic acid binding Ig-like lectin 10 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, sialic acid binding Ig-like lectin 10
Identity 15620
Gene SIGLEC10
Long gene name sialic acid binding Ig like lectin 10
Synonyms gene name sialic acid binding Ig-like lectin 10
Synonyms name sialic acid binding Ig-like lectin 10 Ig-like lectin 7 siglec-like gene 2
Locus 19q13, 41
Discovery year 2001-06-29
GenBank acession AF310233
Entrez gene record 89790
Pubmed identfication 11284738
RefSeq identity NM_033130
Classification C2-set domain containing Sialic acid binding Ig like lectins V-set domain containing
Havana BLAST/BLAT OTTHUMG00000165521

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