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SIGLEC10 Antibody, Biotin Conjugated

SIGLEC10 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SIGLEC10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIGLEC10
SpecificityThis is a highly specific antibody against SIGLEC10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SIGLEC10
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background In the immune response, It preferentially binds to alpha2, SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation, The protein is expressed by peripheral blood leukocytes (eosinophils, The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules, monocytes and a natural killer cell subpopulation), 3- or 2, 6-linked sialic acid, SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SIGLEC-10 SLG2 PRO940 MGC126774
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSIGLEC10 Conjugated
Short name Conjugated, SIGLEC10 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, sialic acid binding Ig-like lectin 10 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Extracellular, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, sialic acid binding Ig-like lectin 10
Identity 15620
Gene SIGLEC10
Long gene name sialic acid binding Ig like lectin 10
Synonyms gene name sialic acid binding Ig-like lectin 10
Synonyms name sialic acid binding Ig-like lectin 10 Ig-like lectin 7 siglec-like gene 2
Locus 19q13, 41
Discovery year 2001-06-29
GenBank acession AF310233
Entrez gene record 89790
Pubmed identfication 11284738
RefSeq identity NM_033130
Classification C2-set domain containing Sialic acid binding Ig like lectins V-set domain containing
Havana BLAST/BLAT OTTHUMG00000165521

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