Name : SIGLEC10 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4517079663
| Long name | Cy3 Conjugated, SIGLEC10 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SIGLEC10 |
| Specificity | This is a highly specific antibody against SIGLEC10 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human SIGLEC10 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | In the immune response, It preferentially binds to alpha2, SIGLEC10 interacts with PTPN6/SHP-1 upon phosphorylation, The protein is expressed by peripheral blood leukocytes (eosinophils, The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules, monocytes and a natural killer cell subpopulation), 3- or 2, 6-linked sialic acid, SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | SIGLEC-10 SLG2 PRO940 MGC126774 |
| Properties | 1 of the SIGLEC10 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SIGLEC10 Conjugated |
| Short name | Conjugated, SIGLEC10 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, sialic acid binding Ig-like lectin 10 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, SIGLEC10 and IDBG-65888 and ENSG00000142512 and 89790, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045087 and innate immune response and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, sialic acid binding Ig-like lectin 10 |
| Identity | 15620 |
| Gene | SIGLEC10 |
| Long gene name | sialic acid binding Ig like lectin 10 |
| Synonyms gene name | sialic acid binding Ig-like lectin 10 |
| Synonyms name | sialic acid binding Ig-like lectin 10 Ig-like lectin 7 siglec-like gene 2 |
| Locus | 19q13, 41 |
| Discovery year | 2001-06-29 |
| GenBank acession | AF310233 |
| Entrez gene record | 89790 |
| Pubmed identfication | 11284738 |
| RefSeq identity | NM_033130 |
| Classification | C2-set domain containing Sialic acid binding Ig like lectins V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000165521 |