Filters

SIM2 Antibody, ALEXA FLUOR 350

SIM2 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, SIM2 Polyclonal Antibody
Also known asAnti-SIM2 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIM2
SpecificityThis is a highly specific antibody against SIM2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIM2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen AhR, Arnt 1, Both SIM1 and SIM2 inhibit AhR/Arnt dimerization, Several PAS domain family members have been identified including AhR, The Ah receptor nuclear translocator protein 1 (Arnt 1) is required for ligand- dependent nuclear translocation of the Ah receptor and is also necessary for Ah receptor binding to the XRE element, The SIM genes are thought to be involved in the directing and regionalization of tissues during development and the SIM2 gene, The aromatic (aryl) hydrocarbon receptor, and single-minded proteins (SIM1 and SIM2), glutathione S-transferase Ya subunit and DT-diaphorase, is a candidate for the gene responsible for Down syndrome, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, thus inhibiting transcriptional activation, which is located on chromosome 21, The Per-Arnt-Sim (PAS) domain was identified as a 270 amino acid motif that mediates associations between various PAS family transcription factors
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms MGC119447 bHLHe15
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetSIM2
Short nameSIM2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, SIM2 (Antibody to)
Alternative techniqueantibodies
Identity 10883
Gene SIM2
Long gene name single-minded family bHLH transcription factor 2
Synonyms gene SIM
Synonyms gene name single-minded (Drosophila) homolog 2 single-minded homolog 2 (Drosophila)
Synonyms name transcription factor SIM2
Locus 21q22, 13
Discovery year 1995-10-02
Entrez gene record 6493
Pubmed identfication 7485157
RefSeq identity NM_009586
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000086637

Similar products

Subscribe to our Newsletter