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SIM2 Antibody, Cy3 Conjugated

SIM2 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, SIM2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIM2
SpecificityThis is a highly specific antibody against SIM2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SIM2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background AhR, Arnt 1, Both SIM1 and SIM2 inhibit AhR/Arnt dimerization, Several PAS domain family members have been identified including AhR, The Ah receptor nuclear translocator protein 1 (Arnt 1) is required for ligand- dependent nuclear translocation of the Ah receptor and is also necessary for Ah receptor binding to the XRE element, The SIM genes are thought to be involved in the directing and regionalization of tissues during development and the SIM2 gene, The aromatic (aryl) hydrocarbon receptor, and single-minded proteins (SIM1 and SIM2), glutathione S-transferase Ya subunit and DT-diaphorase, is a candidate for the gene responsible for Down syndrome, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, thus inhibiting transcriptional activation, which is located on chromosome 21, The Per-Arnt-Sim (PAS) domain was identified as a 270 amino acid motif that mediates associations between various PAS family transcription factors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms MGC119447 bHLHe15
Properties 1 of the SIM2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSIM2 Conjugated
Short name Conjugated, SIM2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, SIM2 (Antibody to)
Alternative techniqueantibodies
Identity 10883
Gene SIM2
Long gene name single-minded family bHLH transcription factor 2
Synonyms gene SIM
Synonyms gene name single-minded (Drosophila) homolog 2 single-minded homolog 2 (Drosophila)
Synonyms name transcription factor SIM2
Locus 21q22, 13
Discovery year 1995-10-02
Entrez gene record 6493
Pubmed identfication 7485157
RefSeq identity NM_009586
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000086637

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