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SIRP Alpha Antibody

SIRP Alpha Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSIRP Alpha Primary Polyclonal Antibody
Also known asSIRP Alpha PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSIRP Alpha
SpecificityThis is a highly specific antibody against SIRP Alpha
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range165-215/504
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD172a
Gene ID number140885
Swiss ProtP78324
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as docking protein and induces translocation of PTPN6, CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells, Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity), Mediates negative regulation of phagocytosis, PTPN11 and other binding partners from the cytosol to the plasma membrane, Supports adhesion of cerebellar neurons, growth factors or insulin, mast cell activation and dendritic cell activation, neurite outgrowth and glial cell attachment, Immunoglobulin-like cell surface receptor for CD47
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, MFR, MYD-1, MYD1, Macrophage fusion receptor, MyD-1 antigen, P84, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, SIRP, SIRPA, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, BIT
Description- or alpha protein sometimes glycoprotein present in blood, The SIRP Alpha Antibody is a &alpha
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSIRP Alpha
Short nameSIRP Alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSIRP a (Antibody to)
Alternative techniqueantibodies
Identity 9662
Gene SIRPA
Long gene name signal regulatory protein alpha
Synonyms gene PTPNS1
Synonyms gene name non-receptor type substrate 1 signal-regulatory protein alpha , protein tyrosine phosphatase
Synonyms SHPS1 SIRP MYD-1 BIT P84 SHPS-1 SIRPalpha CD172a SIRPalpha2 MFR SIRP-ALPHA-1
Locus 20p13
Discovery year 1999-03-19
GenBank acession D86043
Entrez gene record 140885
Pubmed identfication 9070220 9062191 16339511
RefSeq identity NM_080792
Classification C1-set domain containing CD molecules Signal regulatory proteins V-set domain containing
Havana BLAST/BLAT OTTHUMG00000031682

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