Name : SIRT5 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3296085308
| Long name | SIRT5 Primary Polyclonal Antibody |
| Also known as | SIRT5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SIRT5 |
| Specificity | This is a highly specific antibody against SIRT5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 120-170/310 |
| Subcellular location | Mitochondrion |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT5 |
| Gene ID number | 23408 |
| Swiss Prot | Q9NXA8 |
| Tested Applications | IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB |
| Recommended dilutions | IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, Activates SOD1 by mediating its desuccinylation, Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro, Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo, leading to reduced reactive oxygen species, thereby increasing CPS1 activity in response to elevated NAD levels during fasting, NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | NAD-dependent protein deacylase sirtuin-5, Regulatory protein SIR2 homolog 5, SIR2-like protein 5, SIRT5, mitochondrial, SIR2L5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SIRT5 |
| Short name | SIRT5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SIRT5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14933 |
| Gene | SIRT5 |
| Long gene name | sirtuin 5 |
| Synonyms gene name | S, cerevisiae) , homolog) 5 sirtuin (silent mating type information regulation 2 homolog) 5 (S, sirtuin (silent mating type information regulation 2, cerevisiae |
| Locus | 6p23 |
| Discovery year | 2001-03-20 |
| GenBank acession | AF083110 |
| Entrez gene record | 23408 |
| Pubmed identfication | 10381378 |
| Classification | Sirtuins |
| Havana BLAST/BLAT | OTTHUMG00000014278 |