Name : SIRT6 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7429182832
| Long name | SIRT6 Primary Polyclonal Antibody |
| Also known as | SIRT6 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SIRT6 |
| Specificity | This is a highly specific antibody against SIRT6 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT6 |
| Gene ID number | 51548 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes, Deacetylation of nucleosomes interferes with RELA binding to target DNA, Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3, May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance, Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle, Modulates cellular senescence and apoptosis, Regulates the production of TNF protein, Required for genomic stability, Required for normal IGF1 serum levels and normal glucose homeostasis, NAD-dependent protein deacetylase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI043036, Mono ADP ribosyltransferase sirtuin 6, NAD-dependent deacetylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, SIR2 like 6, SIR2 like protein 6, SIR2-like protein 6, SIR2L6, SIR6_HUMAN, SIRT 6, SIRT6, Sir2 related protein type 6, Sirtuin 6, Sirtuin silent mating type information regulation 2 homolog 6 S, Sirtuin type 6, Sirtuin6, cerevisiae, 2810449N18Rik |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SIRT6 |
| Short name | SIRT6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SIRT6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14934 |
| Gene | SIRT6 |
| Long gene name | sirtuin 6 |
| Synonyms gene name | S, cerevisiae, cerevisiae) , homolog) 6 sirtuin (silent mating type information regulation 2 homolog) 6 (S, sirtuin (silent mating type information regulation 2 |
| Locus | 19p13, 3 |
| Discovery year | 2001-03-20 |
| GenBank acession | AF233396 |
| Entrez gene record | 51548 |
| Pubmed identfication | 10873683 |
| Classification | Sirtuins |
| Havana BLAST/BLAT | OTTHUMG00000181847 |