Name : SIX2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7011504630
| Long name | SIX2 Primary Polyclonal Antibody |
| Also known as | SIX2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SIX2 |
| Specificity | This is a highly specific antibody against SIX2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIX2 |
| Gene ID number | 10736 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It has been demonstrated that alterations to homeobox-containing genes may result in cancer, Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, Six1 expression has been shown to be absent or low in normal adult tissues, Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint, Six2, Six2 is highly expressed in fetal tissues but expression is limited in adult tissues, Six4 (AREC3) and Six5 bind to the same DNA sequence, although it is expressed in several tumor types, including breast carcinoma, indicating that they may regulate the same target genes, such as myogenin, The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | OTTHUMP00000201649, SIX homeobox 2, SIX2_HUMAN, Sine oculis homeobox Drosophila homolog 2, Sine oculis homeobox homolog 2, Sine oculis homeobox homolog 2 Drosophila, Six2, Homeobox protein SIX2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SIX2 |
| Short name | SIX2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SIX2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10888 |
| Gene | SIX2 |
| Long gene name | SIX homeobox 2 |
| Synonyms gene name | sine oculis homeobox (Drosophila) homolog 2 sine oculis homeobox homolog 2 (Drosophila) |
| Locus | 2p21 |
| Discovery year | 1999-04-15 |
| GenBank acession | AF136939 |
| Entrez gene record | 10736 |
| Classification | SINE class homeoboxes |
| Havana BLAST/BLAT | OTTHUMG00000152421 |