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SIX2 Antibody, Biotin Conjugated

SIX2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SIX2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSIX2
SpecificityThis is a highly specific antibody against SIX2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SIX2
Gene ID number10736
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It has been demonstrated that alterations to homeobox-containing genes may result in cancer, Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, Six1 expression has been shown to be absent or low in normal adult tissues, Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint, Six2, Six2 is highly expressed in fetal tissues but expression is limited in adult tissues, Six4 (AREC3) and Six5 bind to the same DNA sequence, although it is expressed in several tumor types, including breast carcinoma, indicating that they may regulate the same target genes, such as myogenin, The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSIX2 Conjugated
Short name Conjugated, SIX2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SIX2 (Antibody to)
Alternative techniqueantibodies
Identity 10888
Gene SIX2
Long gene name SIX homeobox 2
Synonyms gene name sine oculis homeobox (Drosophila) homolog 2 sine oculis homeobox homolog 2 (Drosophila)
Locus 2p21
Discovery year 1999-04-15
GenBank acession AF136939
Entrez gene record 10736
Classification SINE class homeoboxes
Havana BLAST/BLAT OTTHUMG00000152421

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