Name : SKA2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7057443562
| Long name | SKA2 Primary Polyclonal Antibody |
| Also known as | SKA2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SKA2 |
| Specificity | This is a highly specific antibody against SKA2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SKA2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Downregulation of Ska2 leads to delayed recruitment of MAD2, Localized to the outer kinetochore and spindle microtubules during cell proliferation, Ska2 is encoded by a gene located on human chromosome 17, Ska2 is essential for spindle checkpoint silencing and exit from mitosis, The Ska1 complex is a component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies, a component of the mitotic spindle checkpoint, a microtubule-binding subcomplex of the outer kinetochore that is critical for proper chromosome segregation, also known as FAM33A, is a 121 amino acid component of the Ska1 complex, to several kinetochores resulting in occasional loss of individual chromosomes from the metaphase plate, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, Ska2 (spindle and kinetochore associated complex subunit 2) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FLJ12758, Family with sequence similarity 33, MGC110975, Protein FAM33A, SKA 2, SKA2, SKA2_HUMAN, Spindle and KT associated 2, Spindle and KT kinetochore associated 2, Spindle and kinetochore associated complex subunit 2, Spindle and kinetochore associated protein 2, Spindle and kinetochore-associated protein 2, member A, FAM33A |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SKA2 |
| Short name | SKA2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SKA2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28006 |
| Gene | SKA2 |
| Long gene name | spindle and kinetochore associated complex subunit 2 |
| Synonyms gene | FAM33A |
| Synonyms gene name | family with sequence similarity 33, member A |
| Synonyms | FLJ12758 |
| Locus | 17q23, 2 |
| Discovery year | 2004-02-24 |
| GenBank acession | BC017873 |
| Entrez gene record | 348235 |
| Pubmed identfication | 17093495 19289083 18583474 |
| RefSeq identity | NM_182620 |
| Havana BLAST/BLAT | OTTHUMG00000179361 |