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SKP2 Antibody, Biotin Conjugated

SKP2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SKP2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSKP2
SpecificityThis is a highly specific antibody against SKP2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range383-424/424
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human Skp2
Gene ID number6502
Swiss ProtQ13309
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CDK9, CDT1, Degradation of CDKN1B/p27kip also requires CKS1, Degradation of TAL1 also requires STUB1, FOXO1, KMT2A/MLL1, Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, RAG2, RBL2, Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2, Recognizes target proteins ORC1, Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition, TOB1 and TAL1, UBP43, and probably MYC, signal transduction and transcription, thereby regulating cell migration, Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FBXL1 FBL1 p45
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSKP2 Conjugated
Short name Conjugated, SKP2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SKP2 (Antibody to)
Alternative techniqueantibodies
Identity 10901
Gene SKP2
Long gene name S-phase kinase associated protein 2
Synonyms gene name E3 ubiquitin protein ligase , S-phase kinase-associated protein 2 (p45) S-phase kinase-associated protein 2
Locus 5p13, 2
Discovery year 1995-12-18
GenBank acession U33761
Entrez gene record 6502
Pubmed identfication 8646875
RefSeq identity NM_005983
Classification F-box and leucine rich repeat proteins
Havana BLAST/BLAT OTTHUMG00000131106

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