SLAP Antibody, Biotin Conjugated

SLAP Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, SLAP Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	SLAP
Specificity	This is a highly specific antibody against SLAP
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human SLAP
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120, A similar putative adapter protein, Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, In general, SH3 domains are often accompanied by SH2 domains of 100 amino acids, Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family, The N- and C-termini, The functions of SH3 domains are not as well defined, and in small adapter proteins, are unique, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, designated Slap, for Src-like adapter protein, frequently linking activated growth factors to putative signal transduction proteins, has been cloned, however, it exists in association with catalytic domains, such as Crk and GRB2, such as spectrin or Myosin, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity, which bind to tyrosine-phosphorylated regions of target proteins, The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	SLAP KIAA1601
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	SLAP Conjugated
Short name	Conjugated, SLAP Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, SLAP (Antibody to)
Alternative technique	antibodies
Identity	16643
Gene	SLMAP
Long gene name	sarcolemma associated protein
Synonyms name	Sarcolemmal-associated protein
Locus	3p14, 3
Discovery year	2001-12-03
GenBank acession	AF100750
Entrez gene record	7871
Pubmed identfication	9405447 11042152
RefSeq identity	NM_007159
Classification	STRIPAK complex
Havana BLAST/BLAT	OTTHUMG00000133764

SLAP Antibody, Biotin Conjugated

SLAP Antibody, Biotin Conjugated size: 0.1ml 333

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