Filters

SLC12A6/KCC3 Antibody

SLC12A6/KCC3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLC12A6/KCC3 Primary Polyclonal Antibody
Also known asSLC12A6/KCC3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLC12A6/KCC3
SpecificityThis is a highly specific antibody against SLC12A6/KCC3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC12A6/KCC3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility, Conversely, In neurons, KCC2 expression is correlated with an inhibitory response to GABA, KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor, KCC3 is not suspected to play a major role in epilepsy, KCC3a and KCC3b, Nitric oxide (NO) donors activate KCCs, The two splice variants of KCC3, The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains, are predominantly expressed in brain and kidney, brain, heart and kidney, lung, respectively, while KCC4 is expressed in muscle, while inhibitors of the cGMP pathway prevent NO donor activation, while the absence of KCC2 is necessary for an unusual excitatory response to GABA, The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Furosemide sensitive KCl cotransporter 3, Gaxp, KCC 3, KCC 3A, KCC 3B, KCC3, KCC3 A, KCC3 B, KCC3A, KCC3B, Potassium chloride cotransporter 3, Potassium chloride cotransporter KCC3a S3, S12A6_HUMAN, SLC12 A6, SLC12A 6, Solute carrier family 12, Solute carrier family 12 potassium/chloride transporters, member 6, member 6, ACCPN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC12A6/KCC3
Short nameSLC12A6/KCC3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSLC12A6/KCC3 (Antibody to)
Alternative techniqueantibodies
Identity 10914
Gene SLC12A6
Long gene name solute carrier family 12 member 6
Synonyms gene KCC3 ACCPN
Synonyms gene name agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome) solute carrier family 12 (potassium/chloride transporter), member 6
Locus 15q14
Discovery year 1999-05-25
GenBank acession AF108831
Entrez gene record 9990
Pubmed identfication 10187864 10347194
RefSeq identity NM_005135
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000129441
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_270

Similar products

Subscribe to our Newsletter