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SLC12A6/KCC3 Antibody, Cy7 Conjugated

SLC12A6/KCC3 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, SLC12A6/KCC3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC12A6/KCC3
SpecificityThis is a highly specific antibody against SLC12A6/KCC3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SLC12A6/KCC3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility, Conversely, In neurons, KCC2 expression is correlated with an inhibitory response to GABA, KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor, KCC3 is not suspected to play a major role in epilepsy, KCC3a and KCC3b, Nitric oxide (NO) donors activate KCCs, The two splice variants of KCC3, The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains, are predominantly expressed in brain and kidney, brain, heart and kidney, lung, respectively, while KCC4 is expressed in muscle, while inhibitors of the cGMP pathway prevent NO donor activation, while the absence of KCC2 is necessary for an unusual excitatory response to GABA, The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetSLC12A6/KCC3 Conjugated
Short name Conjugated, SLC12A6/KCC3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, SLC12A6/KCC3 (Antibody to)
Alternative techniqueantibodies
Identity 10914
Gene SLC12A6
Long gene name solute carrier family 12 member 6
Synonyms gene KCC3 ACCPN
Synonyms gene name agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome) solute carrier family 12 (potassium/chloride transporter), member 6
Locus 15q14
Discovery year 1999-05-25
GenBank acession AF108831
Entrez gene record 9990
Pubmed identfication 10187864 10347194
RefSeq identity NM_005135
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000129441
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database LRG_270

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