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SLC26A6 Antibody , FITC Conjugated

SLC26A6 Antibody , FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, SLC26A6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC26A6
SpecificityThis is a highly specific antibody against SLC26A6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range438-484/759
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SLC26A6
Gene ID number65010
Swiss ProtQ9BXS9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, Function in multiple exchange modes involving pairs of these anions, Isoform 4: Apical membrane chloride-bicarbonate exchanger, Its association with carbonic anhydrase CA2 forms a bicarbonate transport metabolon, Mediates also intestinal chloride absorption and oxalate secretion, Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney, Plays a role in sperm capacitation by increasing intracellular pH, The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, Transepithelial oxalate secretion, and hence will dilute and alkalinize protein-rich acinar secretion, bicarbonate, chloride-formate, chloride-oxalate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner, formate and hydroxyl ion and divalent anions like sulfate and oxalate, hence maximizes the local concentration of bicarbonate at the transporter site, oxalate-formate, oxalate-sulfate and chloride-formate exchange, possibly by providing a bicarbonate import pathway, thereby preventing hyperoxaluria and calcium oxalate urolithiasis, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, which include chloride-bicarbonate, Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms DKFZp586E1422
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC26A6 Conjugated
Short nameSLC26A6 Antibody FITC Conjugated
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SLC26A6 (Antibody to)
Alternative techniqueantibodies
Identity 14472
Gene SLC26A6
Long gene name solute carrier family 26 member 6
Synonyms gene name member 6 , member 6 solute carrier family 26 (anion exchanger), solute carrier family 26
Synonyms name pendrin-like protein 1 pendrin L1 sulfate anion transporter anion transporter 1
Locus 3p21, 31
Discovery year 2001-01-25
GenBank acession AF279265
Entrez gene record 65010
Pubmed identfication 11087667 11247665
RefSeq identity NM_022911
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000186381

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