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SLC39A6 Antibody

SLC39A6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLC39A6 Primary Polyclonal Antibody
Also known asSLC39A6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLC39A6
SpecificityThis is a highly specific antibody against SLC39A6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC39A6
Gene ID number25800
Swiss ProtQ13433
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activated estrogen receptors are thought to regulate LIV-1 expression at the level of transcription, Conversely, LIV-1 is a member of the ZIP transporter protein family which consists of 14 members that transport zinc, LIV-1 is a multi-pass cell membrane protein that is 749 amino acids in length and is expressed abundantly in breast, LIV-1 is thought to be important for zinc uptake in neuroblastoma cells and may also be crucial for maintaining zinc homeostasis, LIV-1 is upregulated in hormone-rich tissue, LIV-1 transports zinc from its position on the plasma membrane into the cytosol of the cell and contains a histidine-rich transmembrane domain which is thought to bind zinc and aid in its transportation, a process which aids in the prevention of cancer and disease, as well as in cells derived from various types of cancers affecting the glands, cervix and lungs, including breast and cervical cancer, indicating a dual role for LIV-1 in tumor suppression, kidney, less aggressive tumors may contain high levels of LIV-1 that could lead to apoptosis, pituitary and corpus callosum, placenta, prostate, via the mRNA precursor to LIV-1 which associates with estrogen receptors that are activated by growth factors and estradiol, where it is thought to affect cell motility and may play an important role in tumor development and metastasis, LIV-1 is expressed as two isoforms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Estrogen-regulated protein LIV-1, LIV1, SLC39A6, Solute carrier family 39 member 6, ZIP-6, ZIP6, Zinc transporter ZIP6, Zrt- and Irt-like protein 6, LIV-1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC39A6
Short nameSLC39A6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSLC39A6 (Antibody to)
Alternative techniqueantibodies
Identity 18607
Gene SLC39A6
Long gene name solute carrier family 39 member 6
Synonyms gene name member 6 , member 6 solute carrier family 39 (zinc transporter), solute carrier family 39 (metal ion transporter)
Synonyms LIV-1
Locus 18q12, 2
Discovery year 2003-10-08
GenBank acession U41060
Entrez gene record 25800
Pubmed identfication 12659941 12839489
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000178965

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