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SLC5A3/SMIT Antibody, ALEXA FLUOR 488

SLC5A3/SMIT Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, SLC5A3/SMIT Polyclonal Antibody
Also known asAnti-SLC5A3/SMIT PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC5A3/SMIT
SpecificityThis is a highly specific antibody against SLC5A3/SMIT
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC5A3/SMIT
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome, In kidney, It is expressed in many human tissues, It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT), SMIT activity maintains intracellular concentrations of myo-inositol, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD), Specifically, The human SMIT protein is encoded by the SLC5A3 gene, but is downregulated in adult rat brain with the exception of the choroid plexus, it is upregulated in response to hypertonic stress, kidney and placenta, signal transduction and osmoregulation, such as brain, where SMIT expression remains high, which maps to chromosome 21q22, 12, Myo-inositol is involved in many important aspects of cellular regulation including membrane structure
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms SMIT SMIT1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SLC5A3/SMIT Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSLC5A3/SMIT
Short nameSLC5A3/SMIT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, SLC5A3/SMIT (Antibody to)
Alternative techniqueantibodies
Identity 11038
Gene SLC5A3
Long gene name solute carrier family 5 member 3
Synonyms gene name member 3 , member 3 solute carrier family 5 (sodium/myo-inositol cotransporter), solute carrier family 5 (inositol transporter)
Locus 21q22, 11
Discovery year 1994-02-15
Entrez gene record 6526
Pubmed identfication 7789985
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000065821

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