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SLC5A3/SMIT Antibody, Cy3 Conjugated

SLC5A3/SMIT Antibody, Cy3 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy3 Conjugated, SLC5A3/SMIT Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC5A3/SMIT
SpecificityThis is a highly specific antibody against SLC5A3/SMIT
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SLC5A3/SMIT
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome, In kidney, It is expressed in many human tissues, It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT), SMIT activity maintains intracellular concentrations of myo-inositol, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD), Specifically, The human SMIT protein is encoded by the SLC5A3 gene, but is downregulated in adult rat brain with the exception of the choroid plexus, it is upregulated in response to hypertonic stress, kidney and placenta, signal transduction and osmoregulation, such as brain, where SMIT expression remains high, which maps to chromosome 21q22, 12, Myo-inositol is involved in many important aspects of cellular regulation including membrane structure
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms SMIT SMIT1
Properties 1 of the SLC5A3/SMIT Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC5A3/SMIT Conjugated
Short name Conjugated, SLC5A3/SMIT Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, SLC5A3/SMIT (Antibody to)
Alternative techniqueantibodies
Identity 11038
Gene SLC5A3
Long gene name solute carrier family 5 member 3
Synonyms gene name member 3 , member 3 solute carrier family 5 (sodium/myo-inositol cotransporter), solute carrier family 5 (inositol transporter)
Locus 21q22, 11
Discovery year 1994-02-15
Entrez gene record 6526
Pubmed identfication 7789985
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000065821

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