Name : SLC6A7/PROT Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8614087228
| Long name | SLC6A7/PROT Primary Polyclonal Antibody |
| Also known as | SLC6A7/PROT PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SLC6A7/PROT |
| Specificity | This is a highly specific antibody against SLC6A7/PROT |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC6A7/PROT |
| Tested Applications | IF(IHC-P), IHC-P, FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Enriched in glutamatergic synaptic terminals, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL), PROT (Sodium-dependent proline transporter), PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals, PROT-mediated proline uptake is inhibited by compounds such as benztropine, These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders, also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain, it is likely that PROT plays an important role in excitatory events of neurotransmission, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients, The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Slc6a7, Sodium-dependent proline transporter, Solute carrier family 6 member 7, SC6A7_HUMAN |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SLC6A7/PROT |
| Short name | SLC6A7/PROT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SLC6A7/PROT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11054 |
| Gene | SLC6A7 |
| Long gene name | solute carrier family 6 member 7 |
| Synonyms gene name | L-proline), member 7 , member 7 solute carrier family 6 (neurotransmitter transporter), solute carrier family 6 (neurotransmitter transporter |
| Synonyms | PROT |
| Synonyms name | brain-specific L-proline transporter sodium-dependent proline transporter |
| Locus | 5q32 |
| Discovery year | 1994-03-16 |
| GenBank acession | S80071 |
| Entrez gene record | 6534 |
| Pubmed identfication | 7651355 |
| RefSeq identity | NM_014228 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000130046 |