Name : SLC6A7/PROT Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9347669874
| Long name | Biotin Conjugated, SLC6A7/PROT Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SLC6A7/PROT |
| Specificity | This is a highly specific antibody against SLC6A7/PROT |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human SLC6A7/PROT |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Enriched in glutamatergic synaptic terminals, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL), PROT (Sodium-dependent proline transporter), PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals, PROT-mediated proline uptake is inhibited by compounds such as benztropine, These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders, also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain, it is likely that PROT plays an important role in excitatory events of neurotransmission, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients, The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | PROT |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SLC6A7/PROT Conjugated |
| Short name | Conjugated, SLC6A7/PROT Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, SLC6A7/PROT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11054 |
| Gene | SLC6A7 |
| Long gene name | solute carrier family 6 member 7 |
| Synonyms gene name | L-proline), member 7 , member 7 solute carrier family 6 (neurotransmitter transporter), solute carrier family 6 (neurotransmitter transporter |
| Synonyms name | brain-specific L-proline transporter sodium-dependent proline transporter |
| Locus | 5q32 |
| Discovery year | 1994-03-16 |
| GenBank acession | S80071 |
| Entrez gene record | 6534 |
| Pubmed identfication | 7651355 |
| RefSeq identity | NM_014228 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000130046 |