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SLC6A7/PROT Antibody, FITC Conjugated

SLC6A7/PROT Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, SLC6A7/PROT Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLC6A7/PROT
SpecificityThis is a highly specific antibody against SLC6A7/PROT
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SLC6A7/PROT
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Enriched in glutamatergic synaptic terminals, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL), PROT (Sodium-dependent proline transporter), PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals, PROT-mediated proline uptake is inhibited by compounds such as benztropine, These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders, also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain, it is likely that PROT plays an important role in excitatory events of neurotransmission, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients, The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PROT
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSLC6A7/PROT Conjugated
Short name FITC Conjugated, SLC6A7/PROT Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SLC6A7/PROT (Antibody to)
Alternative techniqueantibodies
Identity 11054
Gene SLC6A7
Long gene name solute carrier family 6 member 7
Synonyms gene name L-proline), member 7 , member 7 solute carrier family 6 (neurotransmitter transporter), solute carrier family 6 (neurotransmitter transporter
Synonyms name brain-specific L-proline transporter sodium-dependent proline transporter
Locus 5q32
Discovery year 1994-03-16
GenBank acession S80071
Entrez gene record 6534
Pubmed identfication 7651355
RefSeq identity NM_014228
Classification Solute carriers
Havana BLAST/BLAT OTTHUMG00000130046

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