Name : SLC6A7/PROT Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9689525918
| Long name | FITC Conjugated, SLC6A7/PROT Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SLC6A7/PROT |
| Specificity | This is a highly specific antibody against SLC6A7/PROT |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human SLC6A7/PROT |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Enriched in glutamatergic synaptic terminals, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL), PROT (Sodium-dependent proline transporter), PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals, PROT-mediated proline uptake is inhibited by compounds such as benztropine, These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders, also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain, it is likely that PROT plays an important role in excitatory events of neurotransmission, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients, The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | PROT |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SLC6A7/PROT Conjugated |
| Short name | FITC Conjugated, SLC6A7/PROT Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, SLC6A7/PROT (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11054 |
| Gene | SLC6A7 |
| Long gene name | solute carrier family 6 member 7 |
| Synonyms gene name | L-proline), member 7 , member 7 solute carrier family 6 (neurotransmitter transporter), solute carrier family 6 (neurotransmitter transporter |
| Synonyms name | brain-specific L-proline transporter sodium-dependent proline transporter |
| Locus | 5q32 |
| Discovery year | 1994-03-16 |
| GenBank acession | S80071 |
| Entrez gene record | 6534 |
| Pubmed identfication | 7651355 |
| RefSeq identity | NM_014228 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000130046 |