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SLITRK2 Antibody

SLITRK2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLITRK2 Primary Polyclonal Antibody
Also known asSLITRK2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLITRK2
SpecificityThis is a highly specific antibody against SLITRK2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLITRK2
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth, Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events, Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia, suggesting that it suppresses neurite outgrowth, with highest levels found in adult cerebral cortex, SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA1854, SLIK2_HUMAN, SLIT and NTRK like protein 2, SLIT and NTRK-like protein 2, SLITL1, SLITRK 2, Slitrk2, CXorf2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLITRK2
Short nameSLITRK2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSLITRK2 (Antibody to)
Alternative techniqueantibodies
Identity 13449
Gene SLITRK2
Long gene name SLIT and NTRK like family member 2
Synonyms gene SLITL1
Synonyms gene name member 2 , slit-like 1 (Drosophila) SLIT and NTRK-like family
Synonyms KIAA1854 CXorf2
Locus Xq27, 3
Discovery year 2004-03-11
GenBank acession Y19205
Entrez gene record 84631
Pubmed identfication 11347906 14557068
RefSeq identity NM_032539
Havana BLAST/BLAT OTTHUMG00000022595
Locus Specific Databases Mental Retardation database

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