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SLK (Tyr530) Antibody

SLK (Tyr530) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSLK (Tyr530) Primary Polyclonal Antibody
Also known asSLK (Tyr530) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSLK Tyr530
SpecificityThis is a highly specific antibody against SLK Tyr530
Modification(s)Phosphorylation
Modification site(s)Tyr530
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530
Gene ID number2534
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Fyn associates with the T-cell antigen receptor and Thy1, Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation, Fyn is expressed predominately in tissues of neuronal and hematopoietic origin, Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation, Fyn is very strongly similar to mouse Fyn, In T cells, Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing, The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR, non-receptor protein tyrosine kinase approximately 59kDa, v-yes and c-src, which belongs to the Src family of cytoplasmic tyrosine kinases, which may act as substrates or regulators of Fyn activity, Fyn is a membrane-associated
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C syn protooncogene, FYN, FYN oncogene related to SRC FGR YESï, MGC45350ï, OKT3 induced calcium influx regulatorï, P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, SYN, Src like kinase, Src yes related novel gene, Src/yes related novel gene, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT, p-Fyn phospho Y530, ¼, ¼, ¼, &rsaquo, &rsaquo, &rsaquo, Fyn phospho Y530
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSLK (Tyr530)
Short nameSLK (Tyr530) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSTE20-like kinase (Tyr530) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342, SLK and IDBG-88663 and ENSG00000065613 and 9748, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, bA16H23, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0046777 and protein autophosphorylation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, 1 and LOSK and se20-9 and STK2, STE20-like kinase
Identity 4037
Gene FYN
Long gene name FYN proto-oncogene, Src family tyrosine kinase
Synonyms gene name FGR, FYN oncogene related to SRC, YES
Synonyms SYN SLK MGC45350
Locus 6q21
Discovery year 1988-08-19
GenBank acession AK056699
Entrez gene record 2534
Pubmed identfication 3526330
Classification SH2 domain containing Src family tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000016305

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