Name : SLK (Tyr530) Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN9621075993
| Long name | Cy7 Conjugated, SLK (Tyr530) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SLK Tyr530 |
| Specificity | This is a highly specific antibody against SLK Tyr530 |
| Modification | Phosphorylation |
| Modification site | Tyr530 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530 |
| Gene ID number | 2534 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Fyn associates with the T-cell antigen receptor and Thy1, Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation, Fyn is expressed predominately in tissues of neuronal and hematopoietic origin, Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation, Fyn is very strongly similar to mouse Fyn, In T cells, Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing, The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR, non-receptor protein tyrosine kinase approximately 59kDa, v-yes and c-src, which belongs to the Src family of cytoplasmic tyrosine kinases, which may act as substrates or regulators of Fyn activity, Fyn is a membrane-associated |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | SYN SLK MGC45350 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | SLK (Tyr530) Conjugated |
| Short name | Conjugated, SLK (Tyr530) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, STE20-like kinase (Tyr530) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342, SLK and IDBG-88663 and ENSG00000065613 and 9748, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, bA16H23, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0046777 and protein autophosphorylation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, 1 and LOSK and se20-9 and STK2, STE20-like kinase |
| Identity | 4037 |
| Gene | FYN |
| Long gene name | FYN proto-oncogene, Src family tyrosine kinase |
| Synonyms gene name | FGR, FYN oncogene related to SRC, YES |
| Locus | 6q21 |
| Discovery year | 1988-08-19 |
| GenBank acession | AK056699 |
| Entrez gene record | 2534 |
| Pubmed identfication | 3526330 |
| Classification | SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT | OTTHUMG00000016305 |