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sLOX 1 Antibody

sLOX 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namesLOX 1 Primary Polyclonal Antibody
Also known assLOX 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigensLOX 1
SpecificityThis is a highly specific antibody against sLOX 1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range230-273/273
Subcellular location Secreted, Extracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human sLOX 1
Gene ID number4973
Swiss ProtP78380
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts as a receptor for advanced glycation end (AGE) products, Also involved in inflammatory process, In addition to binding oxLDL, Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, activated platelets, apoptotic cells and both Gram-negative and Gram-positive bacteria, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, monocyte adhesion and apoptosis, monocytes, pro-oxidative conditions and apoptosis, resulting in pro-inflammatory responses, thereby participating in cell-mediated antigen cross-presentation, Receptor that mediates the recognition
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-type lectin domain family 8 member A, CLEC8A, LOX-1, LOXIN, Lectin-like oxLDL receptor 1, Lectin-like oxidized LDL receptor 1, Lectin-type oxidized LDL receptor 1, OLR1, Ox-LDL receptor 1, Oxidized low-density lipoprotein receptor 1, SCARE1, SLOX1, hLOX-1, LOX1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetsLOX 1
Short namesLOX 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesLOX 1 (Antibody to)
Alternative techniqueantibodies

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