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SLUG Antibody, ALEXA FLUOR 647

SLUG Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, SLUG Polyclonal Antibody
Also known asAnti-SLUG PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSLUG
SpecificityThis is a highly specific antibody against SLUG
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/268
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Slug
Gene ID Number6591
Swiss ProtO43623
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts, Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes, Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, In epidermal keratinocytes, Involved in osteoblast maturation, Involved in the generation and migration of neural crest cells, Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes, Plays a role in mediating RAF1-induced transcriptional repression of the TJ protein, Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis, Represses BRCA2 expression by binding to its E2-box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells, Represses E-Cadherin/CDH1 transcription via E-box elements, binds to the E-box in ITGA3 promoter and represses its transcription, in osteoblasts, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity), respectively, Transcriptional repressor that modulates both activator-dependent and basal transcription
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms SLUGH1 SNAIL2 SLUGH
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SLUG Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetSLUG
Short nameSLUG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, SLUG (Antibody to)
Alternative techniqueantibodies
Identity 11094
Gene SNAI2
Long gene name snail family transcriptional repressor 2
Synonyms gene SLUG
Synonyms gene name slug homolog, zinc finger protein (chicken) snail homolog 2 (Drosophila) snail family zinc finger 2
Locus 8q11, 21
Discovery year 1998-07-03
GenBank acession U97060
Entrez gene record 6591
Pubmed identfication 9337409 9721220
RefSeq identity NM_003068
Classification Zinc fingers C2H2-type SNAG transcriptional repressors
Havana BLAST/BLAT OTTHUMG00000149912

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