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Smac Antibody / Diablo

Smac Antibody / Diablo size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSmac / Diablo
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the Smac antibody should be determined by the researcher
Intented useThis Smac antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9NR28
PurityAntigen affinity
Description A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64, Alternative splicing results in multiple transcript variants encoding different isoforms, Overexpression of the encoded protein sensitizes tumor cells to apoptosis, The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, also referred to as second mitochondria-derived activator of caspases or SMAC, and allows activation of caspases by binding to inhibitor of apoptosis proteins, is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12, Diablo homolog (DIABLO)
ImmunogenAmino acids 56-239 of human Smac/Diablo were used as the immunogen for the Smac antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Smac antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSmac / Diablo
Short nameSmac Antibody / Diablo
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name IAP-binding mitochondrial protein, Smac (Antibody to) / diablo
Alternative techniqueantibodies

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