| Long name | SMAD1 Primary Polyclonal Antibody |
| Also known as | SMAD1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SMAD1 |
| Specificity | This antibody may cross react with AKAP6 due to a few animo acid sequence similarity, This is a highly specific antibody against SMAD1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 185-220/465 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMAD1 |
| Gene ID number | 4086 |
| Swiss Prot | Q15797 |
| Tested Applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression, SMAD1 is a receptor-regulated SMAD (R-SMAD), SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1, Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BSP-1, JV4-1, JV41, MAD homolog 1, MADH1, MADR1, Mad-related protein 1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, SMAD 1, SMAD family member 1, Smad1, Transforming growth factor-beta-signaling protein 1, hSMAD1, BSP1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SMAD1 |
| Short name | SMAD1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SMAD family member 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BSP-1 and BSP1 and JV4-1 and JV41 and MADH1 and MADR1, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007183 and SMAD protein complex assembly and biological process this GO :0007276 and gamete generation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010656 and negative regulation of muscle cell apoptotic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030509 and BMP signaling pathway and biological process this GO :0030618 and transforming growth factor beta receptor, SMAD1 and IDBG-39936 and ENSG00000170365 and 4086, SMAD1 and IDBG-629431 and ENSBTAG00000002835 and 540488, Smad1 and IDBG-170516 and ENSMUSG00000031681 and 17125, nuclei, pathway-specific cytoplasmic mediator activity, pathway-specific cytoplasmic mediator activity and also this GO :0042802: identical protein binding and also this GO :0046872: metal ion binding and also this GO :0070410: co-SMAD binding and also this GO :0070411: I-SMAD binding, pathway-specific cytoplasmic mediator activity and molecular function this GO :0030901 and midbrain development and biological process this GO :0030902 and hindbrain development and biological process this GO :0031053 and primary miRNA processing and biological process this GO :0042060 and wound healing and biological process this GO :0042493 and response to drug and biological process this GO :0042592 and homeostatic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050775 and positive regulation of dendrite morphogenesis and biological process this GO :0051216 and cartilage development and biological process this GO :0060038 and cardiac muscle cell proliferation and biological process this GO :0060348 and bone development and biological process this GO :0061036 and positive regulation of cartilage development and biological process this GO :0070410 and co-SMAD binding and molecular function this GO :0070411 and I-SMAD binding and molecular function this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :1901522 and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and biological process, this GO :0000165 and MAPK cascade and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001657 and ureteric bud development and biological process this GO :0001710 and mesodermal cell fate commitment and biological process this GO :0001822 and kidney development and biological process this GO :0002051 and osteoblast fate commitment and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005637 and nuclear inner membrane and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005057: receptor signaling protein activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding and also this GO :0030618: transforming growth factor beta receptor, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005057: receptor signaling protein activity, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, this GO :0030618: transforming growth factor beta receptor, this GO :0042802: identical protein binding, this GO :0046872: metal ion binding, this GO :0070410: co-SMAD binding, this GO :0070411: I-SMAD binding, transforming growth factor beta receptor, SMAD family member 1 |
| Identity | 6767 |
| Gene | SMAD1 |
| Long gene name | SMAD family member 1 |
| Synonyms gene | MADH1 |
| Synonyms gene name | MAD, mothers against DPP homolog 1 (Drosophila) , mothers against decapentaplegic homolog 1 (Drosophila) SMAD |
| Synonyms | MADR1 JV4-1 |
| Locus | 4q31, 21 |
| Discovery year | 1996-11-15 |
| GenBank acession | U59423 |
| Entrez gene record | 4086 |
| Pubmed identfication | 8653785 8673135 |
| RefSeq identity | NM_005900 |
| Classification | SMAD family |
| Havana BLAST/BLAT | OTTHUMG00000161592 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue