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Smad2 (7A5) Monoclonal Antibody

Smad2 (7A5) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSmad2 (7A5) Monoclonal Antibody
Also known asSmad2 (7A5) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSmad2
SpecificityThis is a highly specific antibody against Smad2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number7A5
Concentration1ug per 1ul
SourceRecombinant human protein purified from E, coli (His-Smad2)
Gene ID number4087
Swiss ProtQ15796
Tested Applications IP, WB
Recommended dilutions0 ug), 1 ug/mL) IP (2, WB (0
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, May act as a tumor suppressor in colorectal carcinoma, Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator, activates transcription, on formation of the SMAD2/SMAD4 complex, Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names JV18-1, MAD homolog 2, MADH2, MADR2, Mad-related protein 2, Mothers against DPP homolog 2, Mothers against decapentaplegic homolog 2, SMAD 2, SMAD family member 2, Smad2, hMAD-2, hSMAD2, JV18
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetSmad2 (7A5) Monoclonal
Short nameSmad2 (7A5) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameSMAD family member 2 (7A5) monoclonal (Antibody to)
Alternative techniqueantibodies
Identity 30215
Gene MACC1
Long gene name MACC1, MET transcriptional regulator
Synonyms gene name metastasis associated in colon cancer 1
Synonyms 7A5 SH3BP4L
Locus 7p21, 1
Discovery year 2008-10-14
Entrez gene record 346389
Pubmed identfication 25738887
RefSeq identity NM_182762
Havana BLAST/BLAT OTTHUMG00000128415

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