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SMAD5 Antibody

SMAD5 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSMAD5
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the SMAD5 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis SMAD5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q99717
PurityAntigen affinity
Description SMAD5 is a receptor-regulated SMAD (R-SMAD), Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase
ImmunogenA portion of amino acids 241-269 from the human protein was used as the immunogen for this SMAD5 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SMAD5 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSMAD5
Short nameSMAD5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSMAD family member 5 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030218 and erythrocyte differentiation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030618 and transforming growth factor beta receptor, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051216 and cartilage development and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0060348 and bone development and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :1901522 and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and biological process, DWFC and JV5-1 and MADH5, SMAD5 and IDBG-45903 and ENSG00000113658 and 4090, Smad5 and IDBG-157537 and ENSMUSG00000021540 and 17129, nuclei, pathway-specific cytoplasmic mediator activity, pathway-specific cytoplasmic mediator activity and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0046872: metal ion binding, pathway-specific cytoplasmic mediator activity and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0043234 and protein complex and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001503 and ossification and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001880 and Mullerian duct regression and biological process this GO :0002051 and osteoblast fate commitment and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005057: receptor signaling protein activity and also this GO :0005515: protein binding and also this GO :0030618: transforming growth factor beta receptor, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005057: receptor signaling protein activity, this GO :0005515: protein binding, this GO :0030618: transforming growth factor beta receptor, this GO :0031625: ubiquitin protein ligase binding, this GO :0046872: metal ion binding, transforming growth factor beta receptor, 69069 and IDBG-645857 and ENSBTAG00000021772 and 768050, SMAD family member 5
Identity 6771
Gene SMAD5
Long gene name SMAD family member 5
Synonyms gene MADH5
Synonyms gene name MAD, mothers against DPP homolog 5 (Drosophila) , mothers against decapentaplegic homolog 5 (Drosophila) SMAD
Synonyms Dwfc JV5-1
Locus 5q31, 1
Discovery year 1997-07-01
GenBank acession U59913
Entrez gene record 4090
Pubmed identfication 8673135
RefSeq identity NM_005903
Classification SMAD family
Havana BLAST/BLAT OTTHUMG00000163212

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