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Smad7 + Smad6 Antibody

Smad7 + Smad6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSmad7 + Smad6 Primary Polyclonal Antibody
Also known asSmad7 + Smad6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSmad7 + Smad6
SpecificityThis is a highly specific antibody against Smad7 + Smad6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/426
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Smad7
Gene ID number4092
Swiss ProtO15105
Tested Applications ELISA, IF(IHC-P), IHC-P, WB
Recommended dilutions ELISA(1:500-1000), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex, Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity), has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access, which promotes its dephosphorylation, Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MAD homolog 7, MAD homolog 8, MADH7, MADH8, Mothers against DPP homolog 7, Mothers against DPP homolog 8, Mothers against decapentaplegic homolog 7, Mothers against decapentaplegic homolog 8, SMAD 7, SMAD family member 7, Smad7, hSMAD7, CRCS3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSmad7 + Smad6
Short nameSmad7 + Smad6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSMAD family member 7 and SMAD family member 6 (Antibody to)
Alternative techniqueantibodies

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