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SMC1 Antibody

SMC1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSMC1 Primary Polyclonal Antibody
Also known asSMC1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSMC1
SpecificityThis is a highly specific antibody against SMC1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range150-200/1233
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMC1
Gene ID number8243
Swiss ProtQ14683
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At anaphase, Central component of cohesin complex, Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint, allowing sister chromatids to segregate, or via its phosphorylation by ATR, the complex is cleaved and dissociates from chromatin, Involved in chromosome cohesion during cell cycle and in DNA repair
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDLS2, DXS423E, KIAA0178, SB1, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1A, SMC1L1, SMC1alpha, SMCB, Structural maintenance of chromosomes protein 1A, 8, SMC1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSMC1
Short nameSMC1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSMC1 (Antibody to)
Alternative techniqueantibodies
Identity 11112
Gene SMC1B
Long gene name structural maintenance of chromosomes 1B
Synonyms gene SMC1L2
Synonyms gene name SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 SMC1 structural maintenance of chromosomes 1-like 2 (yeast)
Synonyms bK268H5
Locus 22q13, 31
Discovery year 2000-01-12
GenBank acession AJ504806
Entrez gene record 27127
Pubmed identfication 10591208 11564881
RefSeq identity NM_148674
Classification Structural maintenance of chromosomes proteins Cohesin complex
Havana BLAST/BLAT OTTHUMG00000151334

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