Name : SMYD2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6498536994
| Long name | SMYD2 Primary Polyclonal Antibody |
| Also known as | SMYD2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SMYD2 |
| Specificity | This is a highly specific antibody against SMYD2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 290-433/433 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMYD2 |
| Gene ID number | 56950 |
| Swiss Prot | Q9NRG4 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Monomethylates 'Lys-370' of p53/TP53, Monomethylates RB1 at 'Lys-860', Shows even higher methyltransferase activity on p53/TP53, Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2), including p53/TP53 and RB1, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53, Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | HSKM-B, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, N-lysine methyltransferase SMYD2, SET and MYND domain-containing protein 2, SMYD2, ZMYND14, KMT3C |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SMYD2 |
| Short name | SMYD2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SMYD2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 20982 |
| Gene | SMYD2 |
| Long gene name | SET and MYND domain containing 2 |
| Synonyms | HSKM-B ZMYND14 KMT3C |
| Locus | 1q32, 3 |
| Discovery year | 2003-04-28 |
| GenBank acession | AF226053 |
| Entrez gene record | 56950 |
| RefSeq identity | NM_020197 |
| Classification | Lysine methyltransferases Zinc fingers MYND-type |
| Havana BLAST/BLAT | OTTHUMG00000037066 |