Name : SMYD3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7302598110
| Long name | SMYD3 Primary Polyclonal Antibody |
| Also known as | SMYD3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SMYD3 |
| Specificity | This is a highly specific antibody against SMYD3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMYD3 |
| Gene ID number | 64754 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 5'-CCCTCC-3', SMYD3 binds to a motif, SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, homeobox genes and genes associated with cell-cycle regulation, present in the promoter region of downstream genes such as Nkx2, which is enhanced in the presence of the heat-shock protein HSP90A, 8, SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | SET and MYND domain containing protein 3, SMYD 3, SMYD3 protein, SMYD3_HUMAN, ZMYND 1, ZMYND1, ZNFN3A1, Zinc finger MYND domain containing 1, Zinc finger MYND domain containing protein 1, Zinc finger protein subfamily 3A MYND domain containing 1, SET and MYND domain containing 3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SMYD3 |
| Short name | SMYD3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SMYD3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15513 |
| Gene | SMYD3 |
| Long gene name | SET and MYND domain containing 3 |
| Synonyms gene | ZNFN3A1 ZMYND1 |
| Synonyms gene name | MYND domain containing 1 , zinc finger |
| Synonyms | KMT3E |
| Locus | 1q44 |
| Discovery year | 2001-04-06 |
| GenBank acession | AK023594 |
| Entrez gene record | 64754 |
| RefSeq identity | NM_022743 |
| Classification | Lysine methyltransferases Zinc fingers MYND-type |
| Havana BLAST/BLAT | OTTHUMG00000040508 |