Name : SMYD3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4213446910
| Long name | Biotin Conjugated, SMYD3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SMYD3 |
| Specificity | This is a highly specific antibody against SMYD3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human SMYD3 |
| Gene ID number | 64754 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 5'-CCCTCC-3', SMYD3 binds to a motif, SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, homeobox genes and genes associated with cell-cycle regulation, present in the promoter region of downstream genes such as Nkx2, which is enhanced in the presence of the heat-shock protein HSP90A, 8, SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | KMT3E |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SMYD3 Conjugated |
| Short name | Conjugated, SMYD3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, SMYD3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15513 |
| Gene | SMYD3 |
| Long gene name | SET and MYND domain containing 3 |
| Synonyms gene | ZNFN3A1 ZMYND1 |
| Synonyms gene name | MYND domain containing 1 , zinc finger |
| Locus | 1q44 |
| Discovery year | 2001-04-06 |
| GenBank acession | AK023594 |
| Entrez gene record | 64754 |
| RefSeq identity | NM_022743 |
| Classification | Lysine methyltransferases Zinc fingers MYND-type |
| Havana BLAST/BLAT | OTTHUMG00000040508 |