Name : SMYD3 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6082869976
| Long name | FITC Conjugated, SMYD3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SMYD3 |
| Specificity | This is a highly specific antibody against SMYD3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human SMYD3 |
| Gene ID number | 64754 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 5'-CCCTCC-3', SMYD3 binds to a motif, SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, homeobox genes and genes associated with cell-cycle regulation, present in the promoter region of downstream genes such as Nkx2, which is enhanced in the presence of the heat-shock protein HSP90A, 8, SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | KMT3E |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SMYD3 Conjugated |
| Short name | FITC Conjugated, SMYD3 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, SMYD3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15513 |
| Gene | SMYD3 |
| Long gene name | SET and MYND domain containing 3 |
| Synonyms gene | ZNFN3A1 ZMYND1 |
| Synonyms gene name | MYND domain containing 1 , zinc finger |
| Locus | 1q44 |
| Discovery year | 2001-04-06 |
| GenBank acession | AK023594 |
| Entrez gene record | 64754 |
| RefSeq identity | NM_022743 |
| Classification | Lysine methyltransferases Zinc fingers MYND-type |
| Havana BLAST/BLAT | OTTHUMG00000040508 |