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SNX6 (335CT6.4.6) Monoclonal Antibody

SNX6 (335CT6.4.6) Monoclonal Antibody size: 0.1ml 328

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 328
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name4, 6) Monoclonal Antibody, SNX6 (335CT6
Also known as4, 6) Monoclonal Antibody, SNX6 (335CT6
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSNX6
SpecificityThis is a highly specific antibody against SNX6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number335CT6, 4, 6
SourceThis SNX6 monoclonal antibody is generated from mouse immunized with SNX6 recombinant protein
Gene ID number58533
Swiss ProtQ9UNH7
Tested ApplicationsWB
Recommended dilutionsWB(1:1000~16000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774), Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988), In association with GIT1 involved in EGFR degradation, Interacts with membranes phosphatidylinositol 3, Involved in E-cadherin sorting and degradation, Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R (PubMed:17148574), May contribute to transcription regulation (Probable), May function as link between transport vesicles and dynactin (Probable), Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network (PubMed:20354142), Promotes lysosomal degradation of CDKN1B (By similarity), The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling, The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable), inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942), 4-bisphosphate and/or phosphatidylinositol 4, 5-bisphosphate (Probable), Involved in several stages of intracellular trafficking
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MSTP010, SNX6, Sorting nexin-6, TRAF4-associated factor 2, TFAF2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target4, 6) Monoclonal, SNX6 (335CT6
Short name4, 6) Monoclonal Antibody, SNX6 (335CT6
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name4, 6) monoclonal (Antibody to), sorting nexin 6 (335CT6
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process, SNX6 and IDBG-4564 and ENSG00000129515 and 58533, SNX6 and IDBG-632423 and ENSBTAG00000012873 and 532685, Snx6 and IDBG-139633 and ENSMUSG00000005656 and 72183, endosome to this GO lgi and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045892 and negative regulation of transcription, nuclei, protein homodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007175 and negative regulation of epidermal growth factor-activated receptor activity and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0034713 and type I transforming growth factor beta receptor binding and molecular function this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042147 and retrograde transport, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0034713: type I transforming growth factor beta receptor binding and also this GO :0035091: phosphatidylinositol binding and also this GO :0042803: protein homodimerization activity, this GO :0034713: type I transforming growth factor beta receptor binding, this GO :0035091: phosphatidylinositol binding, this GO :0042803: protein homodimerization activity, sorting nexin 6
Identity 14970
Gene SNX6
Long gene name sorting nexin 6
Locus 14q13, 1
Discovery year 2001-04-10
GenBank acession AF121856
Entrez gene record 58533
Pubmed identfication 11279102
Classification Sorting nexins PX-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000140213

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