Filters

SOCS3 Antibody

SOCS3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSOCS3 Primary Polyclonal Antibody
Also known asSOCS3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSOCS3
SpecificityThis is a highly specific antibody against SOCS3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range180-215/225
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Socs 3
Gene ID number9021
Swiss ProtO14543
Tested Applications ELISA, FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions ELISA(1:500-1000), FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binding to JAK2 inhibits its kinase activity, GCSF and leptin receptors, IL12, Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp13, LIF, Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Regulates IL-6 signaling in vivo (By similarity), Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells, SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway, Seems to recognize IL6ST (By similarity), Suppresses fetal liver erythropoiesis, erythropoietin, insulin, SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ATOD4, CIS-3, Cish3, Cytokine-inducible SH2 protein 3, SOCS-3, SOCS3, SSI-3, SSI3, STAT-induced STAT inhibitor 3, Suppressor of cytokine signaling 3, CIS3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSOCS3
Short nameSOCS3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesuppressor on cytokine signaling 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ATOD4 and CIS3 and Cish3 and SOCS-3 and SSI-3 and SSI3, Cytoplasm, SOCS3 and IDBG-647946 and ENSBTAG00000008441 and 282081, SOCS3 and IDBG-70676 and ENSG00000184557 and 9021, Socs3 and IDBG-214604 and ENSMUSG00000053113 and 12702, protein binding, this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060670 and branching involved in labyrinthine layer morphogenesis and biological process this GO :0060674 and placenta blood vessel development and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060708 and spongiotrophoblast differentiation and biological process, this GO :0004860: protein kinase inhibitor activity, this GO :0004860: protein kinase inhibitor activity and also this GO :0005515: protein binding, this GO :0005515: protein binding, suppressor of cytokine signaling 3
Identity 19391
Gene SOCS3
Long gene name suppressor of cytokine signaling 3
Synonyms SSI-3 CIS3 SOCS-3 Cish3
Locus 17q25, 3
Discovery year 2002-11-13
GenBank acession AB004904
Entrez gene record 9021
Pubmed identfication 9266833 9344848
Classification Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000177513
Locus Specific Databases LRG_619

Similar products

Subscribe to our Newsletter