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SOCS4 Antibody

SOCS4 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSOCS4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis SOCS4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8WXH5
PurityAntigen affinity
Description Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR, Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, [UniProt], SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction
ImmunogenA portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SOCS4 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSOCS4
Short nameSOCS4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesuppressor on cytokine signaling 4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target SOCS4 and IDBG-646714 and ENSBTAG00000021988 and 540412, SOCS4 and IDBG-7209 and ENSG00000180008 and 122809, Socs4 and IDBG-154333 and ENSMUSG00000048379 and 67296, multiple, this GO :0007175 and negative regulation of epidermal growth factor-activated receptor activity and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040008 and regulation of growth and biological process, suppressor of cytokine signaling 4
Identity 19392
Gene SOCS4
Long gene name suppressor of cytokine signaling 4
Synonyms gene SOCS7
Synonyms gene name suppressor of cytokine signaling 7
Locus 14q22, 3
Discovery year 2002-11-11
GenBank acession AF424815
Entrez gene record 122809
Pubmed identfication 12076535 10500304
Classification Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000140311

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