Name : SOCS7 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3101566105
| Long name | SOCS7 Primary Polyclonal Antibody |
| Also known as | SOCS7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SOCS7 |
| Specificity | This is a highly specific antibody against SOCS7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 190-240/581 |
| Subcellular location | Membrane bound, Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SOCS7 |
| Gene ID number | 30837 |
| Swiss Prot | O14512 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation, Inhibits also prolactin, May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity), growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA, Regulates signaling cascades probably through protein ubiquitination and/or sequestration |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Ash and phospholipase C gamma-binding protein, NAP-4, NCKAP4, Nck, Nck-associated protein 4, SOCS-7, SOCS6, SOCS7, Suppressor of cytokine signaling 7, NAP4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SOCS7 |
| Short name | SOCS7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SOCS7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19392 |
| Gene | SOCS4 |
| Long gene name | suppressor of cytokine signaling 4 |
| Synonyms gene | SOCS7 |
| Synonyms gene name | suppressor of cytokine signaling 7 |
| Locus | 14q22, 3 |
| Discovery year | 2002-11-11 |
| GenBank acession | AF424815 |
| Entrez gene record | 122809 |
| Pubmed identfication | 12076535 10500304 |
| Classification | Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000140311 |