Name : SOCS7 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7242104258
| Long name | ALEXA FLUOR 647 Conjugated, SOCS7 Polyclonal Antibody |
| Also known as | Anti-SOCS7 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SOCS7 |
| Specificity | This is a highly specific antibody against SOCS7 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 190-240/581 |
| Subcellular location | Membrane bound, Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SOCS7 |
| Gene ID Number | 30837 |
| Swiss Prot | O14512 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation, Inhibits also prolactin, May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity), growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA, Regulates signaling cascades probably through protein ubiquitination and/or sequestration |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SOCS7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | SOCS7 |
| Short name | SOCS7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, SOCS7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19392 |
| Gene | SOCS4 |
| Long gene name | suppressor of cytokine signaling 4 |
| Synonyms gene | SOCS7 |
| Synonyms gene name | suppressor of cytokine signaling 7 |
| Locus | 14q22, 3 |
| Discovery year | 2002-11-11 |
| GenBank acession | AF424815 |
| Entrez gene record | 122809 |
| Pubmed identfication | 12076535 10500304 |
| Classification | Suppressors of cytokine signaling SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000140311 |