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SOCS7 Antibody, Biotin Conjugated

SOCS7 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SOCS7 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSOCS7
SpecificityThis is a highly specific antibody against SOCS7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range190-240/581
Subcellular location Membrane bound, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human SOCS7
Gene ID number30837
Swiss ProtO14512
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation, Inhibits also prolactin, May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity), growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA, Regulates signaling cascades probably through protein ubiquitination and/or sequestration
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSOCS7 Conjugated
Short name Conjugated, SOCS7 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SOCS7 (Antibody to)
Alternative techniqueantibodies
Identity 19392
Gene SOCS4
Long gene name suppressor of cytokine signaling 4
Synonyms gene SOCS7
Synonyms gene name suppressor of cytokine signaling 7
Locus 14q22, 3
Discovery year 2002-11-11
GenBank acession AF424815
Entrez gene record 122809
Pubmed identfication 12076535 10500304
Classification Suppressors of cytokine signaling SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000140311

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