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SORCS1 Antibody, Biotin Conjugated

SORCS1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SORCS1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSORCS1
SpecificityThis is a highly specific antibody against SORCS1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SORCS1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues, Alternative splicing of murine SorCS1 also results in four isoforms, Human SorCS1 is detected in fetal and infant brain and in fetal retina, In the developing and mature central nervous system, It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex, Murine isoform 1 is highly expressed in brain and at lower levels in heart, Murine isoform 2 is highly expressed in liver and at lower levels in heart, SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain, based on a common VPS10 domain, brain, kidney and testis, liver and kidney, non-overlapping pattern, partially overlapping functions in the central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, which is the hallmark of the SorCS receptor family, There are three sorCS genes that have diverse
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms sorCS1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSORCS1 Conjugated
Short name Conjugated, SORCS1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SORCS1 (Antibody to)
Alternative techniqueantibodies
Identity 16697
Gene SORCS1
Long gene name sortilin related VPS10 domain containing receptor 1
Synonyms gene name sortilin-related VPS10 domain containing receptor 1
Locus 10q25, 1
Discovery year 2004-04-20
GenBank acession AF284756
Entrez gene record 114815
Pubmed identfication 11499680
RefSeq identity NM_052918
Havana BLAST/BLAT OTTHUMG00000019018

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